Carmela Dominguez Chambers, 88, of Radford, passed away Thursday, March 20, 2025. She was born in Mercedes, Texas, the daughter of the late Genevieve Dominguez Bogoski. She attended Pan American College at the University of Texas and retired from Carilion with over 20 years of service. She took pride in being part of a U. S. Marine family. Carmela was preceded in death by her mother; and her beloved husband of 43 years, Donald Gray Chambers. Survivors include her daughters and sons-in-law, Audrey and Steve Walters of Lumber City, Ga., Cynthia and Theron Lester of Riner, Va., and Diane and Steve Mack of Radford, Va.; son and daughter-in-law, Donald and Cara Chambers of Salisbury, N.C.; grandchildren, Ainsley (Joe) Posillico, Christopher Chambers, Harrison Chambers Jimmy (Heather) Walters, Stephanie Thomas, and Lisa Bivins; 6 great grandchildren; 4 great great grandchildren; special dog, Bailey; and many other relatives and friends. The family will welcome friends from 2 until 6 p.m. on Sunday, March 23, 2025, at the family home, 319 Third Street, Radford, VA 24141. In lieu of flowers, please consider donations to the American Cancer Association or The Radford Humane Society. The Chambers family is in the care of Mullins Funeral Home & Crematory in Radford, Virginia. www.mullinsfuneralhome.com Visitation Sunday, March 23, 2025 2:00 PM - 6:00 PM Family Home 319 Third Street Radford,VA 24141